More than a dozen residents have been displaced by a fire at a multi-purpose complex in Westhampton

The American Red Cross responded to the victims of a fire that broke out in the apartments of a three-story building on Main Street in Westhampton Beach, officials said.

The Westhampton Beach Fire Department responded to the fire at a commercial and residential building on Main Street at about 5:20 a.m., said John Neely, a volunteer with the department’s fire police division. Fire departments from Center Moriches, Eastport, East Moriches, East Quogue, Flanders, Hampton Bays, Riverhead, Southampton and Quogue were also called to the fire.

“It looked like almost the entire building was on fire when we got there,” Neely said. “It took about an hour to get the fire under control and put it out. He continued to appear in various places. It was difficult to extinguish the fire.”

No one was injured in the incident, Neely said, adding that all residents of apartments on the second and third floors of the building have self-evacuated. According to his estimates, more than a dozen residents were displaced.

“It’s not habitable at all,” Neely said of the two floors of apartments.

The fire did not damage the buildings of Main Street on both sides of it, separated by narrow lanes.

“Crews made an outstanding stop given the conditions they encountered,” Westhampton Beach Fire Chief Darryl Schunk said in a statement. “They definitely saved the nearby buildings.”

The scene has been turned over to the Southampton Town Fire Marshal for investigation, Neely said. The Westhampton Beach Fire Department was used as a shelter for displaced residents assisted by Suffolk County Emergency Management and the American Red Cross.

A trio of clothing and accessories boutiques on the building’s lower floor — Nibi MTK, Tola and Palmer and Purchase — suffered water damage as firefighters battled the blaze, Neely said.

“Firefighters covered a lot of the stock, they were trying to save it, but they were pouring water on the top two floors,” Neely said. “You can imagine how much water seeps down.”

The Nibi MTK store “will be closed indefinitely,” the store announced on Instagram Friday morning in a post that included photos of the fire. In similar posts, under a video of Friday morning’s scene, Tola announced it would be “closing for the foreseeable future,” while Palmer and Purchase said “we’ll be back.”